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raltegravir

Detailed Prescribing Information

 

Raltegravir = Isentress
Dosing Forms 400 mg tablets
Dosing 400 mg twice a day
Hepatic insufficiency: No adjustment is necessary for mild to moderate hepatic impairment.  There is no information regarding severe hepatic insufficiency.
Renal insufficiency: No adjustment needed
Food dependence May be taken with or without food
Adverse Effects Side effects appear to be very similar to placebo
Interactions Rifampin reduces raltegravir levels and should not be used with raltegravir.
Contraindications Rifampin should not be used with raltegravir due to interaction (see above).
Suggested laboratory evaluations Based on background antiretroviral therapy
Warnings None
Full Prescribing Information http://www.isentress.com

 

 

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Fusion Inhibitors
enfuvirtide
Co-Receptor Inhibitors
maraviroc
Integrase inhibitors
raltegravir
 

 

Quick Menu / Table of Contents
Introduction Principles Management NRTI Info NNRTI Info
PI Info Fusion Inhibitors Coreceptor Inhibitors Integrase Inhibitors Drug Summary
Investigational Adherence Lab Evaluation Resistance Tests PEP
Antiretroviral Tables OI Prevention Vaccinations TB Therapy Hepatitis Therapy
OI Diagnosis OI Therapy Bibliography Links Palliative Therapy


Updated 10.17.2007