raltegravir |
Detailed Prescribing Information |
Raltegravir = Isentress | |
Dosing Forms | 400 mg tablets |
Dosing | 400 mg twice a day |
Hepatic insufficiency: No adjustment is necessary for mild to moderate hepatic impairment. There is no information regarding severe hepatic insufficiency. | |
Renal insufficiency: No adjustment needed | |
Food dependence | May be taken with or without food |
Adverse Effects | Side effects appear to be very similar to placebo |
Interactions | Rifampin reduces raltegravir levels and should not be used with raltegravir. |
Contraindications | Rifampin should not be used with raltegravir due to interaction (see above). |
Suggested laboratory evaluations | Based on background antiretroviral therapy |
Warnings | None |
Full Prescribing Information | http://www.isentress.com |
Links to Antiretroviral Sections (click on anything) |
Nucleoside & Nucleotide Reverse Transcriptase Inhibitors (NRTI) |
AZT | ddC | ddI | d4T | 3TC | ABC | FTC | TDF | Combivir | Trizivir | Epzicom | Truvada | Atripla |
Nonnucleoside Reverse Transcriptase Inhibitors (NNRTI) |
efavirenz | nevirapine | delavirdine | etravirine |
Protease Inhibitors (PI) | Boosted Protease Inhibitors |
saquinavir | indinavir | ritonavir | nelfinavir | amprenavir | lopinavir + ritonavir | atazanavir | fosamprenavir | tipranavir |
Fusion Inhibitors |
enfuvirtide |
Co-Receptor Inhibitors |
maraviroc |
Integrase inhibitors |
raltegravir |
Updated 10.17.2007